Impact of Intrathecal Morphine on Sleep Apnea Syndrome

Impact of Intrathecal Morphine on Sleep Apnea Syndrome After Hip Arthroplasty Performed Under Spinal Anaesthesia

Intrathecal morphine is commonly used as an analgesic adjunct for hip arthroplasty performed under spinal anaesthesia. Sleep apnea syndrome is a condition that affects up to 10% of the patients. Effect of intrathecal hydrophilic opioids on the frequency and duration of apneic episodes is unknown. The objective of this randomised controlled trial is to investigate the effect of intrathecal morphine and surgery on apneic episodes.

Inclusion Criteria:

• physical status I - III
• patients scheduled to undergo hip arthroplasty

Exclusion Criteria:

• planned surgical duration more than 3 hours
• contraindication to spinal anaesthesia
• severe respiratory disease
• patient known and treated for sleep apnea syndrome