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This is a safety and efficacy study of botulinum toxin type A in subjects with primary axillary hyperhidrosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dose A | Experimental | Botulinum toxin type A |
|
| Dose B | Experimental | Botulinum toxin type A |
|
| Dose C | Placebo Comparator | Placebo comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Botulinum toxin type A | Biological | Botulinum toxin type A, Dose A, Topical |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Hyperhidrosis Disease Severity Scale (HDSS) | Improvement at follow-up in the experimental groups compared to the placebo group | Week 4 |
| Gravimetry | The amount of sweat measured gravimetrically | Week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Dermatology Life Quality Index (DLQI) | Week 4 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Francisco | California | 94117 | United States |
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| ID | Term |
|---|---|
| D006945 | Hyperhidrosis |
| ID | Term |
|---|---|
| D013543 | Sweat Gland Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D019274 | Botulinum Toxins, Type A |
| ID | Term |
|---|---|
| D001905 | Botulinum Toxins |
| D008666 | Metalloendopeptidases |
| D010450 | Endopeptidases |
| D010447 | Peptide Hydrolases |
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| Botulinum toxin type A |
| Biological |
Botulinum toxin type A, Dose B, Topical |
|
| Placebo comparator | Biological | Placebo, Dose C, Topical |
|
| D006867 |
| Hydrolases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D045726 | Metalloproteases |
| D001426 | Bacterial Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D001427 | Bacterial Toxins |
| D014118 | Toxins, Biological |
| D001685 | Biological Factors |