Study of Botulinum Toxin in Patients With Primary Hyperhidrosis

OBJECTIVES:

I. Determine the optimal dose of botulinum toxin necessary to decrease sweating in patients with primary hyperhidrosis.

PROTOCOL OUTLINE:

Patients receive injections of botulinum toxin in the clinical trial for 6 months. Patients undergo an iodine starch test and a sympathetic skin response test to assess the efficacy of the drug. Patients also complete questionnaires to evaluate the amount of sweating.

• Diagnosis of hyperhidrosis
• Excessive sweating in the hands, feet, armpits, forehead, or body