In this study the investigators treat PM oligometastatic patients with SBRT. Our objective is to evaluate rate of local control of treated lesions in patients treated with Intensity Modulated Radiation Therapy (IMRT) using Volumetric Modulated Arc Therapy (VMAT) for lung metastases from STS.

The investigators started to treat PM oligometastatic patients with Stereotactic Body Radiotherapy.

The investigators objective is to evaluate rate of local control of treated lesions in patients treated with Intensity Modulated Radiation Therapy (IMRT) using Volumetric Modulated Arc Therapy (VMAT) for lung metastases from soft-tissue sarcomas. Overall and disease free survival will be evaluated as secondary endpoints.

Inclusion Criteria:

• Age 18 anni -85 years
• PS according to ECOG 0-2
• Histopathologically confirmation of soft tissue sarcoma
• Metastatic lung lesion less than 4
• Controlled primary tumor and other metastatic lesions
• Metastatic lesion less than 5 such as the definition of oligometastatic patients
• Written informed consent
• Contraindication to surgical resection
• Estimated survival ≥ 3 months
• Absence of progressive disease longer than 6 months
• No chemotherapy was given for at least 3 months after SBRT
• Maximum diameter ≤ 5 cm

Exclusion Criteria:

• Prior thorax radiation therapy
• Age > 85 years
• PS according to ECOG >2
• Pregnant women
• Maximum diameter ≥ 5.1 cm
• Total volume of lung lesion greater than 1/3 of the whole pulmonary parenchima

Patients affected by soft-tissue sarcomas with lung metastases unsuitable for surgery