Does Endometrial Injury Improve Intrauterine Insemination Outcome?

Endometrial Injury May Increase the Pregnancy Rate in Patients Undergoing Intrauterine Insemination

The investigator suggests that local endometrial injury using pipelle catheter performed in the follicular phase (cycle day 5, 6 or 7) of the stimulation cycle may improve the pregnancy rates among patients undergoing intrauterine insemination.

In a selected group of patients with repeated implantation failure, endometrial injury in the preceding cycle may improve ICSI outcome.

Little is known about the efficacy of this procedure in improving intrauterine insemination outcome.

Also little is known about the effect of this procedure if done in the stimulation cycle weather in ICSI or intrauterine insemination cycles.

Inclusion Criteria:

• 18 - 38 years.
• patent fallopian tunes.
• mild male factor.
• anovulation.
• unexplained infertility.

Exclusion Criteria:

• indications for ICSI.
• evidence of pelvic inflammatory disease.