Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study evaluates the incidence of hepatic encephalopathy between covered stent of diameter of 7mm and 8mm in TIPS(transjugular intrahepatic portosystemic stent shunt ).Half of the participants will receive stent of diameter of 7mm ,while the other half will receive stent of diameter of 8mm.
TIPS is effective in the treatment of hemorrhage of digestive tract and intractable ascites,which are the complications of cirrhosis. At present, the high incidence of hepatic encephalopathy has been a major problem after TIPS. The high incidence rate of hepatic encephalopathy was closly associated with the diameter of the stent. We often use the stent of diameter 8mm in TIPS.In this study, we try to use the stent of smaller diameter of 7mm in TIPS,and compare the incidence of hepatic encephalopathy between the stent of diameter of 7mm and 8mm .
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the stent of diameter of 7mm | Experimental | Procedure/Surgery:Jugular vein puncture and catheterization. Device:RUPS-100(COOK Company)sheath ,7mm balloon,Pigtail catheter,the stent of diameter of 7mm (Bard,Fluency) Drug(including placebo):No Biological/Vaccine:No |
|
| the stent of diameter of 8mm | Other | Procedure/Surgery:Jugular vein puncture and catheterization. Device:RUPS-100(COOK Company)sheath ,8mm balloon,Pigtail catheter,the stent of diameter of 8mm (Bard,Fluency) Drug(including placebo):No Biological/Vaccine:No |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| the stent of diameter of 7mm | Device | 108 patients use the stent of diameter of 7mm in TIPS |
|
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of hepatic encephalopathy after TIPS | The incidence of hepatic encephalopathy after TIPS in 7day,1,3,6,12month | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| the incidence of shunt restenosis after TIPS | The incidence of shunt restenosis after TIPS in 7day,1,3,6,12month | 1 year |
| the recurrence rate of gastrointestinal bleeding after TIPS | The recurrence rate of gastrointestinal bleeding after TIPS in 7day,1,3,6,12month |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jianli Xu, MD PhD | Beijing Shijitan Hospital, Capital Medical University | Study Chair |
Not provided
Not provided
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| ID | Term |
|---|---|
| D004066 | Digestive System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| the stent of diameter of 8mm | Device | 108 patients use the stent of diameter of 8mm in TIPS |
|
| 1 year |
| Portal venous pressure before and afterTIPS | Portal venous pressure before and afterTIPS. | 1 year |
| liver function in different periods | liver function during different periods before and after TIPS in 7day,1,3,6,12month | 1 year |
| blood ammonia in different periods | blood ammonia before and after TIPS in 7day,1,3,6,12month | 1 year |
| jaundice index in different periods | jaundice index before and after TIPS in 7day,1,3,6,12month | 1 year |
| platelet count in different periods | platelet count before and after TIPS in 7day,1,3,6,12month | 1 year |