Effect of Ginger Supplement on Non-alcoholic Fatty Liver

The hypothesis of this study was that ginger supplement consumption can be introduced as a new therapeutic strategy for non-alcoholic fatty liver disease through the improved body antioxidant activity, reduced levels of inflammation and insulin resistance. A randomized double-blind study was designed to evaluate this hypothesis in order to examine the effectiveness of ginger supplement in patients with non-alcoholic fatty liver disease.

Inclusion Criteria:

• presence of steatosis on ultrasound examination
• high concentration of liver enzyme (alanine aminotransferase (ALT) greater than normal range of 1.5 times)

Exclusion Criteria:

• various types of hepatitis
• diabetes mellitus
• cancer inherited disorders affecting liver condition (storage disorders of iron, copper, and others)
• non-treated hypothyroidism
• using alcohol
• consumption of phenytoin amoxyfan and lithium
• using minerals multivitamin supplements such as vitamin E, vitamin D, supplements made from Silybum marianum extract like livergol
• weight loss surgery in the last year or strict diets to weight loss in the past three months pregnancy
• lactation
• autoimmune diseases