Penetration and Compartimentation of HIV

Penetration and Compartimentation of HIV in Genital Mucosa

Genital mucosa is the main way of HIV penetration. Many cells can be involved (epithelial cells, Langerhans cells) and antibodies may also play a critical role. The investigators' study aims to precise the role of each type of cells, the interaction cell-cell and cell-antibodies.

At inclusion, men will have a two blood sampling tubes of 10 ml each, a saliva sample and a sample of sperm and women will have a two blood sampling tubes of 10 ml each, a saliva sample and a sampling cervicovaginal secretions

Inclusion Criteria:

• Adults (> 18 year-old) HIV positive,
• HIV-CV> 1000 cp/ml,

Exclusion Criteria:

• children