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| Name | Class |
|---|---|
| Peking University Third Hospital | OTHER |
| Utrecht University | OTHER |
This study aimed to assess the impact of air filtration on indoor air quality and cardio-pulmonary health in residents living in high outdoor pollution settings in Beijing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active-mode | Active Comparator | Air purifier in active-mode |
|
| Sham-mode | Sham Comparator | Air purifier in sham-mode |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| air purifier | Other | filtration units randomly allocated to active- and sham-mode in 20 recruited households for four weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| respiratory inflammation | analyzed EBC pH and inflammation biomarkers 8-isoprostane and nitrite and nitrate | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| systemic inflammation | analyzed systemic inflammation biomarkers C-reaction Protein, Blood coagulation factor fibrinogen (Fib), Interleukin (IL) -8, -1β, -6, -10, -12p70 and tumor necrosis factor-α (TNF-α) | 4 weeks |
| oxidative stress |
| Measure | Description | Time Frame |
|---|---|---|
| lung function | lung function test (FEV1, FEV1 %predicted, FEV1/FVC, 176 maximum midexpiratory flow (MMEF), MMEF %predicted) using an Aspirometer | 4 weeks |
| autonomic function | twelve-hour ambulatory electrocardiogram (ECG) and blood pressure (BP) were monitored |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Wei Huang, PhD | Peking University School of Public Health | Principal Investigator |
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| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| D061808 | Air Filters |
| ID | Term |
|---|---|
| D005374 | Filtration |
| D002623 | Chemistry Techniques, Analytical |
| D008919 | Investigative Techniques |
| D004864 | Equipment and Supplies |
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analyzed systemic oxidative stress biomarker urinary 8-hydroxy-2-deoxyguanosine (8-OHdG)
| 4 weeks |
| 4 weeks |