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To evaluate the values of portosystemic shunt and other interventional radiology approaches for treatment of symptomatic portal hypertension in patients with cavernous transformation of portal vein.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transhepatic portosystemic shunt | Experimental | Patients with cavernous transformation of portal vein undergo transhepatic portalsystemic shunt and other interventional radiology treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transhepatic portosystemic shunt | Procedure | Portal vein (PV) was punctured with a 22-gauge chiba needle. A 0.018-inch guidewire was advanced through the needle into PV lumen. The needle was exchanged and a 6-French sheath inserted over the wire. Then middle hepatic vein (MHV) was punctured with a 20-gauge reformed needle through the transhepatic sheath. Another 0.018-inch guidewire was advanced through the needle into right internal jugular vein and then snared out of body. A 0.035-inch, 260-cm-long stiff shaft wire was introduced through the transjugular sheath and manipulated into main portal vein (MPV) and then into SMV. The parenchymal tract was dilated with balloon catheter, then one or more bare metal stents and one or more covered stents were inserted to line the parenchymal tract. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence Rate of Gastrointestinal Bleeding | No gastrointestinal bleeding proved by patients' symptoms (If the patients had the history of gastrointestinal bleeding before) | 1 month |
| Ascites Volume (mL) | No ascites proved by CT scanning or ultrasound (If the patients had the history of ascites before) | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zaibo Jiang, MD. | Contact | +86 020 85252066 | jiangzaibo@aliyun.com |
| Name | Affiliation | Role |
|---|---|---|
| Zaibo Jiang, MD. | Sun Yat-sen University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Radiology | Recruiting | Guangzhou | Guangdong | 510000 | China |
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|
| 6-French sheath | Device |
|
| 22-gauge chiba needle | Device |
|
| 260-cm-long stiff shaft wire | Device |
|
| Balloon catheter | Device |
|
| Bare metal stent | Device |
|
| Covered stent | Device |
|
| ID | Term |
|---|---|
| C563407 | Portal Vein, Cavernous Transformation Of |
| D006975 | Hypertension, Portal |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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