Treatment of Infected Surgical Wounds With Negative Pressure Topical Therapy and Instillation (With or Without Antiseptic) Versus no Instillation

Treatment of Infected Surgical Wounds With Negative Pressure Topical Therapy and Instillation (With or Without Antiseptic) Versus no Instillation

The objective of this study is to evaluate the effectiveness of PTNi therapy versus PTN therapy without instillation in the treatment of infected surgical wounds. Investigators mean to verify differences of effectiveness between the different types of instilled substances, normal saline versus Amukine Med 0.5%.

Inclusion Criteria:

• Patients with infected surgical wounds.
• Patient age greater than or equal to 18 years.
• Patients who have given informed consent to the enrollment in the trial and to the processing of personal data.

Exclusion Criteria:

• Patients unable of consent.
• Patients affected by serious medical conditions that, according to the investigator's opinion, represent a contraindication to the study participation.
• Patients affected by wounds with exposition of blood vessels, sutures, organs or nerves and open wounds in mediastinum or abdomen.
• Patients with malignancy at the wound.
• Patients with untreated osteomyelitis.
• Patients with enteric and unexplored fistulas.
• Patients with necrotic tissue and eschar.
• Immunocompromised patients or in treatment with corticosteroids.
• Suspected or known allergic diathesis to the product of medication.
• Patients with coagulation disease.