Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.

Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated in Healthy Subjects and Patients With Frontotemporal Dementia. Pilot Phase.

The purpose of this study is to provide relevant quantitative evaluation of apathy close to real life situation by means of a multimodal sensor system integrated.

The investigators try to measure the amount of goal-directed behaviour and to detect the pattern of apathy. The main objective of this pilot phase is to select the variables of goal-directed behaviour from the list of metrics providing by the multimodal acquisition system in healthy subjects and patients with frontotemporal dementia.

Inclusion Criteria:

• Diagnosis of Frontotemporal Dementia (FTD) according to diagnostic criteria reported by Rascovsky et al. (2011).
• Understanding of the instructions and capacity to realize the cognitive tasks.
• Capacity to read, to understand and to sign legal document of information
• Capacity for informed consent for research, capacity to sign consent
• MMSE score > 20
• Absence of other cerebral pathology.
• Absence of psychiatric disease interfering with the assessment of the tests
• Absence of excessive psychotropic use
• Access to National Healthcare Insurance
• Accompanied with a caregiver

Exclusion Criteria:

• Excessive psychotropic use
• Incapacity or refusal to realize the experimental tasks
• Subject deprived of freedom by an administrative or court order
• Subject under legal protective measure.
• Incapacity for informed consent for research
• Participation in another biomedical research
• Airway obstruction risk
• Reduction of activity not attributable to another chronic pathological condition