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All consecutive patients admitted in ILBS from MAY 2015 to DECEMBER 2016. Decompensated cirrhosis patients will be randomized into Group 1: MVP (Moderate Volume Paracentesis) of less than 5 litres with iv albumin at a dose 8 gms/l of ascitic fluid Group 1: MVP (Moderate Volume Paracentesis) of less than 5 litres without albumin .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Albumin | Experimental | MVP (Moderate Volume Paracentesis) of less than 5 liters with iv albumin at a dose 8 gms/l of ascitic fluid. |
|
| No Albumin | Active Comparator | MVP(Moderate Volume Paracentesis) of less than 5 liters without albumin. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Albumin | Drug | MVP of less than 5 liters with iv albumin at a dose 8 gms/L of ascitic fluid. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of PICD (Paracentesis Induced Circulatory Dysfunction). | 1 Year |
| Measure | Description | Time Frame |
|---|---|---|
| Survival | 28 days | |
| Total number of patients develop Hepatorenal Syndrome. | 1 Year | |
| Total number of patients develop hyponatremia. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Liver and Biliary Sciences | New Delhi | National Capital Territory of Delhi | 110070 | India |
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| ascitic fluid |
| Drug |
|
| 1 Year |
| Changes in plasma Renin activity. | 1 Year |
| Changes in aldosterone with volume of ascitic fluid tap. | 1 year |
| ID | Term |
|---|---|
| D000418 | Albumins |
| ID | Term |
|---|---|
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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