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| Name | Class |
|---|---|
| Manitoba Harvest | OTHER |
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The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control.
The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control. The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 20g Hemp Protein Shake | Experimental | Hemp protein shake, 20 grams, given once at beginning of acute trial. |
|
| 40 g Hemp Protein | Experimental | Hemp protein shake, 40 grams, given once, at beginning of acute trial. |
|
| 20 g Soybean Protein Shake | Active Comparator | Soybean protein shake, 20 grams, given once, at beginning of acute trial. |
|
| 40 g Soybean Protein | Experimental | Soybean protein shake, 40 grams, given once, at beginning of acute trial. |
|
| Control Shake | Placebo Comparator | Non-protein control shake, given once, at beginning of acute trial. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hemp Shake | Dietary Supplement | Hemp Protein |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma Glucose and Insulin Concentrations | Measured in blood using intravenous catheter at 12 time points, used to calculate area under curve (AUC). Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits. (Composite measure) | 0-200 minutes |
| Appetite | Measured by VAS Questionnaire. | 0-200 minutes |
| Food Intake | Measured by fixed energy meal. | 0-200 minutes |
| Blood Pressure | Measured by automated bood pressure cuff. | 0-200 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Palatability of Treatments and Meal | Measured by VAS Questionnaire. | 5-80 minutes |
| Physical Comfort | Measured by VAS Questionnaire. | 0-200 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Peter Jones, Ph.D. | University of Manitoba, Richardson Centre for Functional Foods and Nutraceuticals | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Richardson Centre for Functional Foods and Nutraceuticals | Winnipeg | Manitoba | R3T 2N2 | Canada |
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| Hemp |
| Dietary Supplement |
Hemp Protein Shake |
|
| Soybean Shake | Dietary Supplement | Soybean Protein |
|
| Soybean | Dietary Supplement | Soybean Protein Shake |
|
| Control | Dietary Supplement | Non-Protein Shake |
|
| Energy/Fatigue | Measured by VAS Questionnaire. | 0-200 minutes |