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| Name | Class |
|---|---|
| Cerebos Asia Pacific Pte Ltd | UNKNOWN |
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The study will investigate if consumption of amino acid mixtures results a change in glycemic response of carbohydrate (white rice) and insulinemic response at different doses and timing (before consumption of carbohydrate).
Healthy male subjects will be served with amino acid mixtures in combinations of two doses and three time points along with white rice as control. The combinations were either low or high levels of amino acid mixtures. This was consumed together or 15 min, 30 min before consumption of white rice. Postprandial blood glucose and plasma insulin concentrations were measured at fasting and every 15 min after consumption of treatment meal until 60 min after the consumption of white rice. Subsequent blood sample were taken at 30 min interval until 210min. The glucose and insulin in the blood will be analysed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| White rice control | Experimental | Subjects will consume white rice as control (50g carbohydrate) |
|
| co-ingest low dose of amino acid | Experimental | Subjects will receive 68 ml of amino acid mixture together with white rice |
|
| co-ingest high dose of amino acid | Experimental | Subjects will receive 136 ml of amino acid mixture together with white rice |
|
| pre-load low dose15 min | Experimental | Subjects will receive 68 ml of amino acid mixture 15 min before consumption of white rice |
|
| pre-load low dose 30 min | Experimental | Subjects will receive 68 ml of amino acid mixture 30 min before consumption of white rice |
|
| pre-load high dose 15 min |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Rice and Amino Acid mixtures | Other | Rice and amino acid mixture |
|
| Measure | Description | Time Frame |
|---|---|---|
| Glycemic response | Blood glucose will be assessed via finger prick during fasting and every 15 minutes for the first 60 min after the consumption white rice and subsequently every 30 min interval until 210 min | 210 minutes post consumption of carbohydrate |
| Insulinemic response | Plasma insulin will be assessed via finger prick during fasting and every 15 minutes for the first 60 min after the consumption white rice and subsequently every 30 min interval until 210 min | 210 minutes post consumption of carbohydrate |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
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Subjects will receive 136 ml of amino acid mixture 15 min before consumption of white rice |
|
| pre-load high dose 30 min | Experimental | Subjects will receive 136 ml of amino acid mixture 30 min before consumption of white rice |
|