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| Name | Class |
|---|---|
| Hunter Holmes Mcguire Veteran Affairs Medical Center | FED |
| Walter Reed Army Medical Center | FED |
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Evaluation of the utility of a multi-modal assessment tool in distinguishing between individuals with and without a history of mild traumatic brain injury.
This was a preliminary validational study of a multi-modal concussion assessment battery incorporating eye-tracking, balance, and neurocognitive tests on a new hardware platform, the Computerized Brain Injury Assessment System (CBIAS). Using receiver operator curve (ROC) analyses, 1) a subset of the most discriminating neuro-physiological assessment tests involving smooth pursuit eye motion (SPEM) tracking errors, corrective saccade counts, a balance score ratio sensitive to vestibular balance performance and two neurocognitive tests of response speed and memory/incidental learning, was identified, 2) the enhancement in discriminatory capability of detecting concussion-related deficits through the combination of the identified subset of assessments was demonstrated, and 3) the effectiveness of a robust and readily implemented global scoring approach was demonstrated for both eye track and balance assessment tests. These results are significant in introducing a comprehensive solution for concussion assessment that incorporates an economical, compact and mobile hardware system and an assessment battery that is multi-modal, time efficient and whose efficacy has been demonstrated on a preliminary basis. This represents a significant step toward the goal of a system capable of making a dependable return-to-play/duty determination based on concussion likelihood.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| mTBI-diagnosed group | Experimental | Subjects diagnosed with mTBI were assessed with a multi-modal assessment system. |
|
| non mTBI-diagnosed group | Experimental | Non-concussed subjects were assessed with a multi-modal assessment system. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Multi-modal assessment system | Device | Subjects were assessed using a multi-modal concussion assessment battery incorporating eye-tracking, balance, and neurocognitive tests |
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| Measure | Description | Time Frame |
|---|---|---|
| Receiver-operator-curve area under the curve (AUC) | Each test's discrimination capability was quantified using AUC and p value | up to 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Martin C. Baruch, PhD | Empirical Technologies Corporation | Principal Investigator |
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| ID | Term |
|---|---|
| D001924 | Brain Concussion |
| D014947 | Wounds and Injuries |
| ID | Term |
|---|---|
| D000070642 | Brain Injuries, Traumatic |
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 | Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D016489 | Head Injuries, Closed |
| D014949 | Wounds, Nonpenetrating |