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| Name | Class |
|---|---|
| Barnes-Jewish Hospital | OTHER |
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The primary outcome of this study is to demonstrate the feasibility of a prehabilitation program at Barnes Jewish Hospital for liver transplant candidates. Those patients who consent to participate in the study and are placed on the transplant list will be randomized into either the control or intervention group. The intervention group receives a personalized home exercise program along with weekly phone calls to provide coaching, mentoring and motivation. Data collected at baseline, post-transplant and, post-transplant follow up will be compared among the two study groups. The secondary outcomes include: normative data of functional measures for patients with end stage liver disease and to determine the effect size for future research on prehabilitation in the patient population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | No Intervention | Subjects will receive standard care both pre and post transplant. | |
| Exercise Group | Experimental | Subjects will receive a personalized home exercise program and regular phone calls from a therapist to monitor and promote activity. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Procedure | Subjects will be given and individualized exercise program. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of a prehabilitation program. | Feasibility will be measured by participation and outcome assessment measures. | 2 Years |
| Measure | Description | Time Frame |
|---|---|---|
| Normative data on Timed Up and Go for patients with end stage liver disease. | Baseline | |
| Normative data on 10 meter walk for patients with end stage liver disease. | Baseline | |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D058625 | End Stage Liver Disease |
| D009043 | Motor Activity |
| D008107 | Liver Diseases |
| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D004066 | Digestive System Diseases |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Normative data on Modified Dynamic Gait Index for patients with end stage liver disease. |
| Baseline |
| Normative data on Five Time Sit to Stand for patients with end stage liver disease. | Baseline |
| Normative data on 6 Minute Walk Test for patients with end stage liver disease. | Baseline |