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The investigators aimed to add flaxseed with high content of n-3 polyunsaturated fatty acids to low fat yogurt to obtain beneficial without adverse effects of it. In this parallel randomized controlled trial the investigators recruited 70 diabetic patients and randomly allocated to control and treatment groups. Participants in treatment group consumed 30 gr flaxseed in 200 gr low fat yogurt, while controls consumed 200 gr just low fat yogurt daily. Lipid profile, fasting blood sugar, glycosylated hemoglobin, systolic and diastolic blood pressure, weight, waist circumference and body mass index were measured at the first and end of the trial.
Nutritionists have concern about consumption of full fat dairy in diabetic patients due to their content of saturated fatty acids. The investigators aimed to add flaxseed with high content of n-3 polyunsaturated fatty acids to low fat yogurt to obtain beneficial without adverse effects of it. In this parallel randomized controlled trial the investigators recruited 70 diabetic patients and randomly allocated to control and treatment groups. Participants in treatment group consumed 30 gr flaxseed in 200 gr low fat yogurt, while controls consumed 200 gr just low fat yogurt daily. Lipid profile, fasting blood sugar, glycosylated hemoglobin, systolic and diastolic blood pressure, weight, waist circumference and body mass index were measured at the first and end of the trial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| low fat yogurt enriched with flaxseed | Experimental | 200 gr low fat yogurt enriched with 30 gr flaxseed |
|
| low fat yogurt | Placebo Comparator | 200 gr low fat yogurt |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| low fat yogurt enriched with flaxseed | Dietary Supplement | daily intake of low fat yogurt enriched with flaxseed for 8 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in values of FBS at 8 week | FBS: Fasting blood sugar | 8 weeks |
| Change from baseline in values of HbA1c at 8 week | HbA1C: glycosylated hemoglobin | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in values of weight at 8 week | 8 weeks | |
| Change from baseline in values of waist circumference at 8 week | 8 weeks | |
| Change from baseline in values of body mass index at 8 week |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31720254 | Derived | Hasaniani N, Rahimlou M, Ramezani Ahmadi A, Mehdizadeh Khalifani A, Alizadeh M. The Effect of Flaxseed Enriched Yogurt on the Glycemic Status and Cardiovascular Risk Factors in Patients with Type 2 Diabetes Mellitus: Randomized, Open-labeled, Controlled Study. Clin Nutr Res. 2019 Oct 2;8(4):284-295. doi: 10.7762/cnr.2019.8.4.284. eCollection 2019 Oct. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D008043 | Linseed Oil |
| ID | Term |
|---|---|
| D005224 | Fats, Unsaturated |
| D005223 | Fats |
| D008055 | Lipids |
| D010938 | Plant Oils |
| D009821 |
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| low fat yogurt | Dietary Supplement | daily intake of low fat yogurt for 8 weeks |
|
| 8 weeks |
| Change from baseline in values of blood pressure at 8 week | Blood pressure: systolic blood pressure, diastolic blood pressure | 8 weeks |
| Change from baseline in values of Lipid profile (Total cholesterol, triglyceride, LDL-C, HDL-C) at 8 week | Lipid profile:Total cholesterol, triglyceride, LDL-C, HDL-C | 8 weeks |
| Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |