Effect of mosapride 30mg/day on the small bowel and colon transit time in patients with chronic constipation or constipated irritable bowel syndrome.

Inclusion Criteria:

• Functional constipation or constipated irritable bowel syndrome patients according to Rome III criteria

Exclusion Criteria:

• Intolerable or hypersensitive to mosapride
• Known Parkinson's ds
• Cardio- or cerebrovascular disease within 3 months
• Malignancy requiring surgery or chemotherapy or radiation within 5 years
• History of GI surgeries except hernia repair, appendectomy, primary closure due to perforation
• Refractory diabetes mellitus/hypertension/thyroid diseases
• Symptomatic heart failure, renal failure, arrhythmia