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| Name | Class |
|---|---|
| Al Baraka Fertility Hospital | OTHER |
| Banon IVF Center Assiut, Egypt | OTHER |
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Comparing the efficacy of tow factors for artificial Oocyte Activation for poor quality Oocytes and Teratozoospermia patients.
The IVF outcome had been varied widely with a good portion of total fertilization failure even after the most advanced procedure for this group of patient Intracytoplasmic Sperm Injection, many factors that had been tested for assisting the failed group of patient to be fertilized artificially like Ca Ionophore, Strontium Chloride and others but we decide to compare the clinically proven factors for the efficacy and safety in a well randomized clinical trial and monitor the embryogenesis and pregnancy within the 2 groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ca Ionophore group | Experimental | Artificial Oocyte activation with Ca Ionophore for 20 min after Intracytoplasmic Sperm Injection |
|
| Strontium Chloride group | Experimental | Artificial Oocyte activation with Strontium Chloride for 60 min after Intracytoplasmic Sperm Injection |
|
| Only Intracytoplasmic Sperm Injection | No Intervention | after Intracytoplasmic Sperm Injection Oocytes will cultured and incubated |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Artificial Oocyte activation | Other |
| ||
| Ca Ionophore |
| Measure | Description | Time Frame |
|---|---|---|
| Pregnancy rate ( % ) | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Blastocyst rate ( % ) | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Al Barka fertility center | Manama | Bahrain | ||||
| Banon Fertility Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30099496 | Derived | Fawzy M, Emad M, Mahran A, Sabry M, Fetih AN, Abdelghafar H, Rasheed S. Artificial oocyte activation with SrCl2 or calcimycin after ICSI improves clinical and embryological outcomes compared with ICSI alone: results of a randomized clinical trial. Hum Reprod. 2018 Sep 1;33(9):1636-1644. doi: 10.1093/humrep/dey258. |
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| ID | Term |
|---|---|
| C025700 | strontium chloride |
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| Drug |
|
| Strontium Chloride | Drug |
|
| Asyut |
| Egypt |
| Ibnsina IVF center | Sohag | Egypt |