Study on the Relationship Between Periodontitis and Renal Disease

Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University

Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.

A total of 200 population is recruited, individuals are divided into four groups according to a periodontal examination and a general physical examination: healthy individuals ,periodontitis, renal disease patients with healthy periodontium, and renal disease patients wth peridontitis. Fasting blood samples and gingival crevicular fluid are collected from all individuals, and inflammatory markers are analysed for the four groups.

Inclusion Criteria:

• all participants were in general good health(except renal disease) and non-smoking

Exclusion Criteria:

• less than 20 teeth in the dentin
• hypertension
• the presence of systemic disease (e.g., diabetes mellitus ,coronary heart disease, liver, or lung disease)
• a history or the symptom of any other acute or chronic infections
• systemic antibiotic treatment within previous 4 weeks
• periodontal treatment within1 month