Sublingual Microcirculation of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope

Population Research of Sublingual Microcirculation Data of Healthy Volunteers by Using the Third Generation Microcirculation Video Microscope

This study will enroll 150 healthy volunteers, and the grouping is as follows: group 20-39 (30 males and 30 females); group 40-59 (30 males and 30 females); and group 60-79 (15 males and 15 females). The sublingual microcirculation will be examined with the incident dark field video microscope (Cytocam，Braedius Battery Powered Transilluminator). The study aims to compare the differences of microcirculation among the three groups and between genders.

Inclusion Criteria:

• Healthy volunteers aged from 20 to 79 years old
• BMI ranged from 18.5 to 27 kg/m2

Exclusion Criteria:

• Systolic blood pressure > 140 mm Hg, diastolic blood pressure > 95 mm Hg, or systolic blood pressure < 90 mm Hg at enrollment

• Body temperature > 37.5 ℃ or < 35.5 ℃ at enrollment

• had been diagnose with any one of the following diseases

  • hypertension
  • diabetes mellitus
  • peripheral arterial occlusive disease
  • coronary arterial disease
  • liver cirrhosis
  • chronic kidney disease
  • stroke
  • anemia
  • asthma
  • chronic bronchitis
  • any metabolic diseases
  • any hematologic disease
  • uncured cancer
  • chronic uncontrolled infection
  • other disease may limit daily activities
  • non-native speakers