Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| University of Nottingham | OTHER |
| Tehran University of Medical Sciences | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of the present study is to evaluate the effect of replacing diet beverages with water on weight loss and biochemical indicators for insulin sensitivity and cardiometabolic risk factors of diabetic obese and overweight female adults when they are in a multidisciplinary weight loss plan.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diet Beverages (DBs) | Experimental | Diet beverages after the main meal+ Diet |
|
| Water | Experimental | Water after the main meal+ Diet |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DBs at the end of the main meal + Diet | Behavioral | Subjects are asked to have 250 ml DBs at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Weight loss | 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Fasting plasma glucose | 24 weeks | |
| Insulin resistance (HOMA) | 24 weeks | |
| Lipid profiles |
Not provided
Inclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Hamid R Farshchi, MD, PhD | NovinDiet Clinic, School of Life Sciences, The University of Nottingham | Study Chair |
| Ameneh Madjd, Dr | NovinDiet Clinic, School of Life Sciences, The University of Nottingham | Principal Investigator |
| Ian A Macdonald, Prof. | School of Life Sciences, The University of Nottingham | Principal Investigator |
| Moira A Taylor, PhD | School of Life Sciences, The University of Nottingham | Principal Investigator |
| Reza Malekzadeh, Prof. | Digestive Disease Research Institute, Tehran University of Medical Sciences | Principal Investigator |
| Alireza Delavari, MD | Digestive Disease Research Institute, Tehran University of Medical Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NovinDiet Clinic | Tehran | 1913635136 | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32449201 | Derived | Lohner S, Kuellenberg de Gaudry D, Toews I, Ferenci T, Meerpohl JJ. Non-nutritive sweeteners for diabetes mellitus. Cochrane Database Syst Rev. 2020 May 25;5(5):CD012885. doi: 10.1002/14651858.CD012885.pub2. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| D050177 | Overweight |
| D009765 | Obesity |
| D003920 | Diabetes Mellitus |
| D015431 | Weight Loss |
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D004032 | Diet |
| ID | Term |
|---|---|
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Water at the end of the main meal+ Diet | Behavioral | Subjects are asked to have 250 ml water at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks. |
|
| 24 weeks |
| Waist circumference | 24 weeks |
| BMI | 24 Weeks |
| HA1C | 24 Weeks |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001836 | Body Weight Changes |
| D006946 | Hyperinsulinism |