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| Name | Class |
|---|---|
| Nestle Waters North America, Inc | UNKNOWN |
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The primary objectives of this clinical trial are to determine if replacing sugar sweetened beverages with water consumption promote weight loss over 6 months in overweight adults and if replacing sugar sweetened beverages with water consumption promote greater weight loss over 6 months relative to replacement with other non-caloric sweetened beverages or control.
The secondary objective is to identify mediators and moderators of the effect of water replacement including hydration status, glucose metabolism, anthropometrics, physical activity, dietary intake and resting metabolic rate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Choices | Other |
| |
| Diet Substitution A | Experimental |
| |
| Diet Substitution B | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary substitution A | Behavioral | Substitution of calorie-dense item with lower calorie choice A |
|
| Measure | Description | Time Frame |
|---|---|---|
| Weight change | 0, 3, 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| urine specific gravity | 0, 3, 6 months | |
| fasting glucose | 0, 3, 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Deborah F Tate, PhD | University of North Carolina, Chapel Hill | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599-7294 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23364015 | Derived | Piernas C, Tate DF, Wang X, Popkin BM. Does diet-beverage intake affect dietary consumption patterns? Results from the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. Am J Clin Nutr. 2013 Mar;97(3):604-11. doi: 10.3945/ajcn.112.048405. Epub 2013 Jan 30. | |
| 22301929 | Derived | Tate DF, Turner-McGrievy G, Lyons E, Stevens J, Erickson K, Polzien K, Diamond M, Wang X, Popkin B. Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial. Am J Clin Nutr. 2012 Mar;95(3):555-63. doi: 10.3945/ajcn.111.026278. Epub 2012 Feb 1. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Dietary Substitution B | Behavioral | Substitution of calorie-dense item with lower calorie option B |
|
| Healthy Choices | Behavioral | Multiple healthy choices presented with self-selection of choices used |
|
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |