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| Name | Class |
|---|---|
| Washington University School of Medicine | OTHER |
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This study will determine the extent of high-sensitivity cardiac troponin (hs-cTn) release in patients without cardiac risk factors undergoing extremity orthopedic surgery. This study will provide important evidence on how to interpret postoperative cardiac troponin elevations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adults without cardiac disease | Extremity orthopedic or trauma surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Extremity orthopedic or trauma surgery | Procedure | hip, leg, shoulder, arm |
|
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative change of high-sensitivity cardiac troponin plasma level | 3 samples:
| 24 hours preoperatively to postoperative day (POD) 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Peak high-sensitivity cardiac troponin plasma level | 3 samples:
| 24 hours preoperatively to POD 1 |
| Incidence rate of high-sensitivity cardiac troponin plasma level elevation |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing extremity surgery without history of cardiovascular disease
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| Name | Affiliation | Role |
|---|---|---|
| Andreas Duma, MD, MSc | Medical University of Vienna | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna | Vienna | 1090 | Austria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29406178 | Derived | Duma A, Wagner C, Titz M, Maleczek M, Hupfl M, Weihs VB, Samaha E, Herkner H, Szekeres T, Mittlboeck M, Scott MG, Jaffe AS, Nagele P. High-sensitivity cardiac troponin T in young, healthy adults undergoing non-cardiac surgery. Br J Anaesth. 2018 Feb;120(2):291-298. doi: 10.1016/j.bja.2017.09.001. Epub 2017 Dec 5. |
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Plasma
3 samples:
| 24 hours preoperatively to POD 1 |