Perioperative Cardiac Troponin Levels in Healthy Adults

Perioperative High-sensitivity Cardiac Troponin Levels in Healthy Adults Undergoing Elective Trauma Surgery

This study will determine the extent of high-sensitivity cardiac troponin (hs-cTn) release in patients without cardiac risk factors undergoing extremity orthopedic surgery. This study will provide important evidence on how to interpret postoperative cardiac troponin elevations.

Inclusion Criteria:

• Age 18-35 years
• Extremity orthopedic or trauma surgery: leg, hip, arm, shoulder.
• Planned overnight hospital admission
• No cardiac risk factors (Lee's Revised Cardiac Risk Index Class 1)
• American Society of Anesthesiologists (ASA) physical status I-II

Exclusion Criteria:

• Any history or symptoms of cardiac disease
• Kidney or liver disease
• Recent or current trauma to the trunk or head
• Persons with increased vulnerability (e.g. cognitive limitations, prisoners,…)
• Pregnancy