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The aim of this study is to gain insight into the etiology of myocardial injury after non cardiac surgery. Furthermore, suspected etiologies were explored and hierarchically classified into most likely cause how this determines prognosis and what factors are associated with improved outcome.
As above
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High sensitive Troponin T | Other | The baseline population will consist of all patients who underwent a form of non-cardiac surgery. Baseline variables, medication use, type of surgery and perioperative hemodynamic and laboratory variables will be extracted from the hospital information system. One year mortality is registered, as well as major vascular events. This is in line with previous publications from our group. The adjudication strategy used for patients with myocardial injury. For the adjudication process minimal two senior anesthesiologists will be invited. Two members with at least one senior anesthesiologist will receive a sample of patients to adjudicate. Together the entire panel will adjudicate all patients. The goal to investigate the differences between the raters. |
| Measure | Description | Time Frame |
|---|---|---|
| Main etiologies elevated troponin T | The primary endpoint is a description of the main etiologies found within patients with an elevated troponin T after non cardiac surgery. | from enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| Differences in adjudication | Differences in the adjudication process between different doctors will be assessed according to intraclass coeficients and Fleisch Kappa | from enrollment |
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Inclusion Criteria:
Exclusion Criteria:
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The population to be studied consists of all non-cardiac surgical patients who underwent surgery at Erasmus MC in the period 2017-2023.
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| Name | Affiliation | Role |
|---|---|---|
| Sanne Hoeks, PhD | Epidemiologist | Study Director |
| Felix van Lier, PhD | Anesthesiologist | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Erasmus Medical Center | Rotterdam | Netherlands |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Sep 26, 2024 | Nov 19, 2024 | Prot_000.pdf |
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