Intra-operative Radiotherapy For Women With Ductal Carcinoma in Situ Breast Cancer

Intra-operative Radiotherapy After Breast-conversing Surgery in Treating Women With Ductal Carcinoma in Situ Breast Cancer

Whether the patients with low grade ductal carcinoma in situ breast cancer should accept radiationtherapy is uncertain.Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Giving radiation during surgery followed by external-beam radiation to the entire breast may kill more tumor cells.The clinical trial is conducting to find out the effectiveness of radiation therapy during surgery in treating women who have undergone breast-conversing surgery for low grade ductal carcinoma in situ breast cancer.

Inclusion Criteria:

• Tumor diameter < 5 cm
• Low grade ductal carcinoma in situ
• Candidate for breast-conserving surgery
• Must have undergone lumpectomy with negative margins or minimal margin involvement
• Currently undergoing re-excision of the biopsy cavity and/or sentinel lymph node biopsy or axillary lymph node dissection
• No evidence of metastatic disease
• Informed consent

Exclusion Criteria:

• No informed consent
• Tumor size > 5 cm
• Intermediate or high grade ductal carcinoma in situ
• Invasive carcinoma
• No indication for a boost