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| Name | Class |
|---|---|
| Universidad de Granada | OTHER |
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There is no conclusive evidence about the effect of intake of protein-enriched drink after and acute high intensity exercise bout on muscle function and damage. The investigators aimed to study the effect of a protein-enriched drink on muscle function recovery following an acute high intensity exercise bout. The present counterbalanced, crossover, and double blind study will involve a total of 12 active men.
Participants will run downhill (-10%) during 30 min at a intensity equivalent to 75-80% of their maximum heart rate (previously determined). After the exercise bout, participants will have either the placebo or the experimental drink. The investigators will measure muscle function and damage-related parameters right after the exercise as well as the three following days. This protocol will be repeated after a wash out period of 3 weeks, where the participants will have the other drink. The investigators will control exercise and diet three weeks before study entry, during the experimental week as the investigators as during the wash out period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Placebo Comparator | 330 ml of commercial protein-enriched drink (2.5 g/100 ml of protein) | |
| Experimental | Experimental | 330 ml of protein-enriched drink (6 g/100 ml of protein) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Protein-enriched drink | Dietary Supplement | Participants will drink 330 ml of a protein-enriched drink (6 g/ml of protein) after a high intensity exercise that induce muscle damage (30 min running downhill with a slope of -10º) |
| Measure | Description | Time Frame |
|---|---|---|
| Isometric muscle strength | Isometric muscle strength of lower limbs at 90% angle. | Change from pre- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drink |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle soreness of lower limbs self-reported by a visual anagogic scale and with an algometer score. | Muscle soreness of the lower limbs will be self-reported by a visual anagogic scale and with an algometer score. | Change from post- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drink |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Federico Lara, PhD | Contact | 0034958240100 | Federico.LaraVilloslada@puleva.es |
| Name | Affiliation | Role |
|---|---|---|
| Federico Lara, PhD | Puleva Biotech | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Biosearch Life | Recruiting | Granada | Granada | 18004 | Spain |
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| ID | Term |
|---|---|
| D003286 | Contracture |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D009135 | Muscular Diseases |
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| Power output assessed with the 30sec. Wingate anaerobic test |
Power output will be assessed with the 30sec. Wingate anaerobic test. |
| Change from post- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drink |
| Creatine kinase | Creatine kinase will be assessed after the protein-enriched drink to assess muscle recovery after a high intensity exercise bout | Change from post- protein-enriched drink to 24, 48 hrs post- protein-enriched drink |
| Urine Creatinine | Concentration of creatinine in urine will be assessed after the protein-enriched drink to assess muscle recovery after a high intensity exercise bout | Change from post- protein-enriched drink to 24, 48 hrs post- protein-enriched drink |
| Resting metabolic rate | Change from pre- protein-enriched drink to 24, 48 and 72 hrs post- protein-enriched drink |
| Time limit (time that the participant is able to run 90% of his determined maximum aerobic velocity) | We will measure the time that the participant is able to run 90% of his determined maximum aerobic velocity | 24hrs after protein-enriched drink |