Penn State TXT2Quit Study

Pilot Randomized Trial of an Automated Smoking Cessation Intervention Via Mobile Phone Text Messages as an Adjunct to Varenicline in Primary Care

This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.

Inclusion Criteria:

• Smoke >4 cigarettes/day for at least 6 months
• Age 21+
• Want to quit and ready to try in next 30 days
• Willing to quit all forms of tobacco (including e-cigs)
• Willing to use Chantix to try to quit
• Have a cell phone able to receive text messages
• Willing to attend 3 visits and use varenicline for smoking cessation
• Plan to live in local area for next 6 months
• Read and write in English
• Women not pregnant and taking steps to avoid
• Able to understand and willing to sign consent

Exclusion Criteria:

• History of allergic reaction or other adverse event while using varenicline
• Used a smoking cessation aid/medicine in past 1 month (including e-cigs)
• Currently pregnant or nursing
• Does not have a mobile phone that can send and receive text messages or unwilling to receive study texts
• Uncontrolled serious mental illness or substance abuse or inpatient treatment for these in the past 6 months
• Uses non-cigarette tobacco products and does not plan to quit all tobacco.
• Has a history of kidney problems or receives dialysis
• Had any thoughts that they would be better off dead or of deliberate self-harm in the prior 4 weeks
• Had a heart attack in the past 4 weeks
• Mental conditions that would prohibit the participant from completing the protocol