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The proposed study is a retrospective, observational study. A group of 5 subjects with the AttuneTM cruciate retaining (CR) fixed bearing total knee arthroplasty (TKA) are analysed during level walking, a deep knee bend, sitting down onto a chair, standing up from a chair and stair descent at least 12 months post-operatively, in terms of 3D fluoroscopic assessed tibio-femoral TKA motion as well as simultaneous skin marker assessed whole leg motion and ground reaction forces. The obtained information helps the manufacturer (DePuy) to evaluate, bring to market and advance the implant. Furthermore the information will be integrated in a model, which will be developed at the Center for Orthopaedic Engineering, University of Denver. By means of this model, different conditions such as the use of an advanced prosthesis design can be simulated and tested.
The objective of this study is in a first step to demonstrate the capability of data collection and analysis of level gait, deep knee bend, sitting down onto a chair, standing up from a chair and stair descent on a limited sample size of five subjects. Secondly to quantify and describe the three-dimensional kinematics for the cruciate retaining (CR), fixed bearing AttuneTM TKA during daily activities such as those mentioned.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational use of fluoroscopy | Radiation |
| Measure | Description | Time Frame |
|---|---|---|
| Relationship between the knee flexion angle and the medial and lateral anterior-posterior translation of the condyles | The primary outcome of this pilot study is the relationship between the knee flexion angle and the medial and lateral anterior-posterior translation of the condyles during level walking, stair descent, standing up from a chair, sitting onto a chair and deep knee bend. | 3 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Prof. Dr. med. Carsten Perka will do the recruitment, since he is the surgeon that worked the most with this implant and therefore also has the biggest population of possibly eligible patients. Furthermore the patients already know and trust him, which could lead to a greater success in the recruitment as well. For these reasons the financial source DePuy Synthes, Johnson and Johnson, requires that the clinical collaborator Prof. Dr. med. Carsten Perka will do the recruitment. He works in the Charité in Berlin, Germany, where he does the recruitment.
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| Name | Affiliation | Role |
|---|---|---|
| Renate List, PhD | ETH Zurich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute for Biomechanics | Zurich | Canton of Zurich | 8093 | Switzerland |
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