Glycaemic and Insulinaemic Responses After Consumption of FOS.

Postprandial Glycaemic and Insulinaemic Responses After Consumption of Dairy Desserts Containing Fructo-oligosaccharides in Adults.

The study aims to evaluate the glycaemic and insulinaemic response of short-chain fructo-oligosaccharides (scFOS) used to replace sugars (e.g. dextrose) in foods.

Inclusion Criteria:

• Body mass index (BMI) between 18.0 and 25.0 kg/m² (included)
• Ready to keep the same volume of physical activity and the same dietary habits during the study and particularly 24 hours before each visit
• Be used to have breakfast
• Non-smoker for at least 3 months
• For the female participant: not being pregnant or breastfeeding and using efficient birth control
• Signed the consent form
• Able to follow the instructions of the study
• Health insured
• Accepted to be included in the National Registry for biomedical research Volunteers (Fichier VRB, Volontaires Recherches Biomédicales).

Exclusion Criteria:

• Fasting blood glucose over 6.1 mmol/L (1.10 g/L) (or diabetes treated or not)
• Fasting blood cholesterol over 6.35 mmol/L
• Fasting blood triglycerides over 1.70 mmol/L (or history of insulinoma)
• Fasting blood insulin under 20 mU/L
• Fasting HbA1c under 7%
• History of hypercholesterolemia, hypertension, diabetes or glucose intolerance treated or not
• History of dietary allergies or coeliac disease
• History of digestive system disease susceptible to modify digestion or absorption like Crohn's disease
• Somatic or psychiatric disorders
• Renal insufficiency (kidney failure)
• SGOT or ALAT over 52.5 U/L
• Smoker
• Consuming more than 3 alcoholic beverage a day
• Weight varied 3 kg the last 3 months