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Patients can potentially monitor disease activity of rheumatoid arthritis (RA) through self-assessed swollen joints (clinical synovitis)joint counts but reliability of joint swelling is poor. The objective is to evaluate the use of education by ultrasound feedback on the ability of patients to assess for clinical synovitis swollen joints in RA.
Design: 6-month single centre randomized controlled trial. Patients: established RA. Intervention: education on self-assessment of joints that included initial brief patient training on tender (TJC) and swollen (SJC) joint counts, followed by US feedback every 3 months versus standard care without education. Patient and physician independently performed 28-joint counts at each visit. Outcome variables: (Primary) Percentage of patients with good agreement with physician derived swollen joints (prevalence-adjusted bias adjusted kappa, PABAK>0.6). Other variables: Agreement in SJC (Bland and Altman 95% limits of agreement), feasibility/patient satisfaction survey and disease activity score (DAS28) at 6 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Education with ultrasonography | Experimental | Intervention includes education of self-assessment of synovitis using ultrasonography as a feedback training tool |
|
| Standard Care | No Intervention | Normal standard care where patients are not taught how to self-assess for synovitis, without ultrasonography a training tool |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Education using ultrasonography as feedback tool | Behavioral | Education using ultrasonography as feedback tool |
|
| Measure | Description | Time Frame |
|---|---|---|
| prevalence-adjusted bias adjusted kappa, PABAK>0.6 | at 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Bland and Altman 95% limits of agreement | swollen joint count agreement | 6 months |
| Level of satisfaction | Likert response, satisfaction survey |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Peter Cheung | National University Hospital, Rheumatology | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25477057 | Derived | Cheung PP, Lahiri M, Teng GG, Lim AY, Lau TC, Lateef A, Mak A, Gossec L, March L. A randomized controlled trial for improving patient self-assessment of synovitis in rheumatoid arthritis with education by ultrasonography: the RAEUS Study. Rheumatology (Oxford). 2015 Jul;54(7):1161-9. doi: 10.1093/rheumatology/keu447. Epub 2014 Dec 3. |
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| 6 months |
| disease activity score in 28 joints (DAS28) | composite score that measures disease activity incorporating tender joint count, swollen joint count, erythrocyte sedimentation rate and patient global assessment | 6 months |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |