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The purpose of this study is to determine if it would be helpful to use advanced MRI imaging techniques to take additional views of the tumor target for radiation treatment planning or treatment follow-up MRI.
The results of this research project will be used to establish a standard MRI protocol specific to each tumor or disease site. An MRI protocol is a list of MR image types that are acquired for each disease site. These images are used to generate the patient's treatment plan.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MRI for treatment planning or follow up | MRI for treatment planning for radiation therapy or those who have completed treatment and are receiving follow up care. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants Successfully Contributing MRI Data | We tested these Advanced MR protocols to evaluate which ones would best visualize the target region. This helped us determine the optimum MR SIM protocols for different sites that became clinical standard. | up to 4 weeks from imaging |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects who are planning to have radiation therapy for their cancer.
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| Name | Affiliation | Role |
|---|---|---|
| Ergun Ahunbay, PhD | Medical College of Wisconsin | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9132820 | Background | Khoo VS, Dearnaley DP, Finnigan DJ, Padhani A, Tanner SF, Leach MO. Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning. Radiother Oncol. 1997 Jan;42(1):1-15. doi: 10.1016/s0167-8140(96)01866-x. |
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158 subjects were enrolled.
420 was the initial estimate but 158 subjects was the accrual
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| ID | Title | Description |
|---|---|---|
| FG000 | MRI for Treatment Planning or Follow up | MRI for treatment planning for radiation therapy or those who have completed treatment and are receiving follow up care. |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
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| ID | Title | Description |
|---|---|---|
| BG000 | MRI for Treatment Planning or Follow up | MRI for treatment planning for radiation therapy or those who have completed treatment and are receiving follow up care. |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Number of Participants Successfully Contributing MRI Data | We tested these Advanced MR protocols to evaluate which ones would best visualize the target region. This helped us determine the optimum MR SIM protocols for different sites that became clinical standard. | Posted | Count of Participants | Participants | up to 4 weeks from imaging |
|
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | MRI for Treatment Planning or Follow up | MRI for treatment planning for radiation therapy or those who have completed treatment and are receiving follow up care. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Ergun Ahunbay | Medical College of Wisconsin | 4148057898 | eahunbay@mcw.edu |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D011471 | Prostatic Neoplasms |
| D012509 | Sarcoma |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D005832 | Genital Diseases, Male |
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| Participants |
|
| Sex: Female, Male | Enrollment open to both genders. | Count of Participants | Participants |
|
| Participants |
|
|
| 0 |
| 158 |
| 0 |
| 158 |
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| D000091662 |
| Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |