Long Protocol and Growth Hormone in Poor Responders

Growth Hormone Adjuvant Therapy With Long Down Regulation Protocol in Poor Responders Undergoing In Vitro Fertilization Cycles: a Randomized Control Trial

The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the addition of growth hormone.

Inclusion Criteria:

• Poor responder females are those who posses two out of these three criteria:
• Female age ≥40 years
• Females who have at least one previous cancelled IVF cycle
• POR according to AFC ≤ 5 or low AMH value.

Exclusion Criteria:

• Females over 45 years
• Females with FSH more than 20 IU/l
• Females with previous ovarian surgery
• Females suffering from causes of infertility other than poor ovarian response
• Females refusing to be enrolled in the study