Genetic Analysis of Childhood Obesity | NCT02326480 | Trialant

Genetic Analysis of Childhood Obesity | NCT02326480 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Syndromic obesity		Identification of genetic causes of obesity
Familial obesity		Identification of genetic causes of obesity	Other: Identification of genetic causes of obesity
Isolated obesity		Identification of genetic causes of obesity	Other: Identification of genetic causes of obesity

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Identification of genetic causes of obesity	Other	A blood test will be performed to the child and his/her parents with the aim of identifying genetic causes of obesity. Different analysis will be as follows: caryotypes, Raindance, whole exome, in order to find potential mutations or new genes associated to this condition

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
To identify the number of mutations or genes involved in genetic causes of Child obesity	Children with obesity and their parents will be recruited to establish genetic causes of obesity. This will allow perform genetic analysis using new approaches for the identification of involved mutations or new candidate genes	first day of enrollement

Secondary Outcomes

Measure	Description	Time Frame
To identify the number of mutations in the population		first day of enrollement
To identify the number of new mutations present in the children's DNA and absent from their parents' genomes	This approach will allow the identification of specific mutations that are present only in affected children but not in their parents

Contacts/Locations Module

Overall Officials

Name	Affiliation	Role
Louise Montagne	Groupement des Hôpitaux de l'Institut Catholique de Lille	Principal Investigator
Philippe Froguel, MD, PhD	UMR CNRS 8199, Institut Pasteur de Lille	Principal Investigator

Condition Browse Module