Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions

Salivary and Serum Levels of Chemerin and MMP-9 in Oral Precancer and Oral Squamous Cell Carcinoma.

45 individuals were subdivided into 3 groups, 15 patients with oral premalignant lesions, 15 patients with oral malignant lesions and 15 control individuals. Levels of chemerin and MMP-9 were evaluated in serum and saliva of these subjects utilizing the ELISA technique.

45 individuals were subdivided into 3 groups, 15 patients suffering from oral premalignant lesions, 15 patients suffering from oral malignant lesions and 15 individuals having age, gender and periodontal status matched with both patients groups acting as a control group. Serum and whole unstimulated saliva samples were collected from all the included groups in order to determine chemerin and MMP-9 in serum and saliva utilizing the ELISA technique.

Inclusion Criteria:

• patients with oral premalignant lesions.
• patients with oral malignant lesions.

Exclusion Criteria:

• any systemic disease other than oral premalignant or malignant lesions. smokers. pregnant females. periodontal diseases.