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| Name | Class |
|---|---|
| Universita di Verona | OTHER |
| Ospedali Riuniti Trieste | OTHER |
| University of Catania | OTHER |
| University of Leicester |
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The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
Improvements in the surgical treatment of coronary artery disease are possible only when implementation of current methods and development of new methods are based on the solid ground of large and reliable clinical data. Furthermore, clinical findings assume even more significance when detected in study populations from different institutions with heterogeneous referral pathways, baseline clinical characteristics and perioperative treatment strategies. The rationale of this European multicenter study is therefore to prospectively collect data on baseline characteristics, operative and anesthesiological methods and postoperative outcome of patients undergoing CABG in eleven cardiac surgery centers from five European countries. This multicenter prospective registrywill provide data to evaluate the prognostic impact of a number of patients' risk factors as well as the efficacy and safety of operative methods and drugs used during the pre-, peri- and postoperative period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coronary artery bypass surgery | Patients undergoing coronary artery bypass surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coronary artery bypass surgery | Procedure | Patients will undergo coronary artery bypass grafting |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Any death occurring after surgery | The outcome measure will be assessed at time points up to 10 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Stroke | Any ischemic brain injury occurring after surgery and lasting > 24 hours | The outcome measure will be assessed at time points up to 10 years after surgery |
| Prolonged use of inotropes | Use of inotropes > 12 hours after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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The study population includes any patient undergoing isolated coronary artery bypass surgery.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fausto Biancari, Professor | Contact | +358407333973 | faustobiancari@yahoo.it |
| Name | Affiliation | Role |
|---|---|---|
| Fausto Biancari, Professor | University of Oulu, Oulu, Finland | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oulu University Hospital | Recruiting | Oulu | Finland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32442254 | Derived | Rubino AS, Nicolini F, Tauriainen T, Demal T, De Feo M, Onorati F, Faggian G, Bancone C, Perrotti A, Chocron S, Dalen M, Santarpino G, Fischlein T, Maselli D, Musumeci F, Santini F, Salsano A, Zanobini M, Saccocci M, Bounader K, Gatti G, Ruggieri VG, Mignosa C, Juvonen T, Mariscalco G, Biancari F. Failure to achieve a satisfactory cardiac outcome after isolated coronary surgery in low-risk patients. Interact Cardiovasc Thorac Surg. 2020 Jul 1;31(1):9-15. doi: 10.1093/icvts/ivaa062. | |
| 31957634 |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| D009203 | Myocardial Infarction |
| D000787 | Angina Pectoris |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D001026 | Coronary Artery Bypass |
| ID | Term |
|---|---|
| D009204 | Myocardial Revascularization |
| D006348 | Cardiac Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| OTHER |
| Centre Hospitalier Universitaire de Besancon | OTHER |
| Karolinska Institutet | OTHER |
| San Camillo Hospital, Rome | OTHER |
| Rennes University Hospital | OTHER |
| S. Anna Hospital | OTHER |
| Paracelsus Medical University | OTHER |
| University of Campania Luigi Vanvitelli | OTHER |
| University of Parma | OTHER |
| University of Bari | OTHER |
| Centro Cardiologico Monzino | OTHER |
| University of Hamburg-Eppendorf | OTHER |
| University of Genova | OTHER |
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| Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Intra-aortic balloon pump | Use of intra-aortic balloon pump for acute heart failure after surgery | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| ECMO | Use of extracorporeal membrane oxygenation for acute heart failure after surgery | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Repeat revascularization | Any repeat myocardial revascularization procedure performed after surgery | The outcome measure will be assessed at time points up to 10 years after surgery |
| Wound infection | Any deep sternal or lower limb wound infection occurring after surgery | Participants will be followed up for 3 months after surgery |
| Blood losses | Amont of blood losses from drainages 12 hours after surgery | Participants will be followed 12 hours after surgery |
| Nadir hematocrit | Lowest hematocrit level during the operation day | Participants will be followed during the operation day |
| Use of blood products | Use of any blood product (red blood cell, fresh frozen plasma, Octaplas, platelets) during the in-hospital stay | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Use of prothrombotic drugs | Perioperative use of cryoprecipitate, PCC and/or rFVIIa for excessive bleeding PCCs Perioperative use of rFVIIa, PCC, cryoprecipitate | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Resternotomy for bleeding | Re-exploration for excessive bleeding | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Atrial fibrillation | New episode of atrial fibrillation requiring or not cardioversion during the in-hospital stay | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Renal replacement therapy | Any renal replacement therapy during the in-hospital stay | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Highest level of serum creatinine | Highest level of serum creatinine during the in-hospital stay | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Myocardial infarction | Myocardial infarction (diagnosed by ECG and troponin monitoring) any time after surgery | The outcome measure will be assessed at time point up to 10 years after surgery |
| Length of stay in the intensive care unit | Length of stay in the intensive care unit after surgery | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Pericardial effusion | Pericardial effusion requiring medical or surgical treatment | Participants will be followed up to 3 months after surgery. |
| Postoperative use of antibiotics | Postoperative use of antibiotics for postoperative infection | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Gastrointestinal complications | Any gastrointestinal complication requiring medical or surgical treatment after surgery | Participants will be followed for the duration of hospital stay (expected: 10 days) |
| Derived |
| Biancari F, Gatti G, Rosato S, Mariscalco G, Pappalardo A, Onorati F, Faggian G, Salsano A, Santini F, Ruggieri VG, Perrotti A, Santarpino G, Fischlein T, Saccocci M, Musumeci F, Rubino AS, De Feo M, Bancone C, Nicolini F, Kinnunen EM, Demal T, D'Errigo P, Juvonen T, Dalen M, Maselli D. Preoperative risk stratification of deep sternal wound infection after coronary surgery. Infect Control Hosp Epidemiol. 2020 Apr;41(4):444-451. doi: 10.1017/ice.2019.375. Epub 2020 Jan 20. |
| 30527774 | Derived | Khodabandeh S, Biancari F, Kinnunen EM, Mariscalco G, Airaksinen J, Gherli R, Gatti G, Demal T, Onorati F, Faggian G, De Feo M, Santarpino G, Rubino AS, Maselli D, Salsano A, Nicolini F, Zanobini M, Ruggieri VG, Bounader K, Perrotti A, Dalen M. Perioperative Bleeding in Patients With Acute Coronary Syndrome Treated With Fondaparinux Versus Low-Molecular-Weight Heparin Before Coronary Artery Bypass Grafting. Am J Cardiol. 2019 Feb 15;123(4):565-570. doi: 10.1016/j.amjcard.2018.11.028. Epub 2018 Nov 24. |
| 30197287 | Derived | Santarpino G, Nicolini F, De Feo M, Dalen M, Fischlein T, Perrotti A, Reichart D, Gatti G, Onorati F, Franzese I, Faggian G, Bancone C, Chocron S, Khodabandeh S, Rubino AS, Maselli D, Nardella S, Gherli R, Salsano A, Zanobini M, Saccocci M, Bounader K, Rosato S, Tauriainen T, Mariscalco G, Airaksinen J, Ruggieri VG, Biancari F. Prognostic Impact of Asymptomatic Carotid Artery Stenosis in Patients Undergoing Coronary Artery Bypass Grafting. Eur J Vasc Endovasc Surg. 2018 Nov;56(5):741-748. doi: 10.1016/j.ejvs.2018.07.042. Epub 2018 Sep 6. |
| 29897529 | Derived | Reichart D, Rosato S, Nammas W, Onorati F, Dalen M, Castro L, Gherli R, Gatti G, Franzese I, Faggian G, De Feo M, Khodabandeh S, Santarpino G, Rubino AS, Maselli D, Nardella S, Salsano A, Nicolini F, Zanobini M, Saccocci M, Bounader K, Kinnunen EM, Tauriainen T, Airaksinen J, Seccareccia F, Mariscalco G, Ruggieri VG, Perrotti A, Biancari F. Clinical frailty scale and outcome after coronary artery bypass grafting. Eur J Cardiothorac Surg. 2018 Dec 1;54(6):1102-1109. doi: 10.1093/ejcts/ezy222. |
| 29440275 | Derived | Mariscalco G, Rosato S, Serraino GF, Maselli D, Dalen M, Airaksinen JKE, Reichart D, Zanobini M, Onorati F, De Feo M, Gherli R, Santarpino G, Rubino AS, Gatti G, Nicolini F, Santini F, Perrotti A, Bruno VD, Ruggieri VG, Biancari F. Prior Percutaneous Coronary Intervention and Mortality in Patients Undergoing Surgical Myocardial Revascularization: Results From the E-CABG (European Multicenter Study on Coronary Artery Bypass Grafting) With a Systematic Review and Meta-Analysis. Circ Cardiovasc Interv. 2018 Feb;11(2):e005650. doi: 10.1161/CIRCINTERVENTIONS.117.005650. |
| 27904903 | Derived | Biancari F, Brascia D, Onorati F, Reichart D, Perrotti A, Ruggieri VG, Santarpino G, Maselli D, Mariscalco G, Gherli R, Rubino AS, De Feo M, Gatti G, Santini F, Dalen M, Saccocci M, Kinnunen EM, Airaksinen JK, D'Errigo P, Rosato S, Nicolini F. Prediction of severe bleeding after coronary surgery: the WILL-BLEED Risk Score. Thromb Haemost. 2017 Feb 28;117(3):445-456. doi: 10.1160/TH16-09-0721. Epub 2016 Dec 1. |
| 26123033 | Derived | Biancari F, Ruggieri VG, Perrotti A, Svenarud P, Dalen M, Onorati F, Faggian G, Santarpino G, Maselli D, Dominici C, Nardella S, Musumeci F, Gherli R, Mariscalco G, Masala N, Rubino AS, Mignosa C, De Feo M, Della Corte A, Bancone C, Chocron S, Gatti G, Gherli T, Kinnunen EM, Juvonen T. European Multicenter Study on Coronary Artery Bypass Grafting (E-CABG registry): Study Protocol for a Prospective Clinical Registry and Proposal of Classification of Postoperative Complications. J Cardiothorac Surg. 2015 Jun 30;10:90. doi: 10.1186/s13019-015-0292-z. |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D002637 | Chest Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D058017 | Vascular Grafting |
| D014656 | Vascular Surgical Procedures |
| D019616 | Thoracic Surgical Procedures |