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| Name | Class |
|---|---|
| Thammasat University | OTHER |
| Srinakharinwirot University | OTHER |
| Mahidol University | OTHER |
| Ministry of Health, Thailand |
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Elderly people usually have systemic diseases and take medications that can cause dry mouth. The purpose of this study is to determine whether continuous use of edible, gel-based artificial saliva in geriatric population with dry mouth problems will reduce signs and symptoms of dry mouth and improve quality of patients' saliva.
A pre-post test trial was conducted in 120 elders with xerostomia. All subjects received a total of 50 ml (10ml x 5 times) OMJ per day. Subjective and objective dry mouth scores, salivary pH, buffering capacity and satisfaction were monitored at 2 weeks and 1 month use, compared to baseline. The data were analyzed by Repeated Measure ANOVA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gel-based artificial saliva | Experimental | Continuous oral intake of edible gel-based artificial saliva (30-50 ml/day) for four weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gel-based artificial saliva | Other | Gel-based artificial saliva is a novel gel-like, edible moisturizing gel designed to relieve dry mouth. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in subjective dry mouth score | The outcome measure (subjective dry mouth score) will be measured before and 2 and 4 weeks after continuous usage of edible gel-based artificial saliva (30-50 ml/day for at least 5 days per week) | baseline, 2 weeks and 4 weeks after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in objective dry mouth score | The outcome measure will be measured before and 2 and 4 weeks after continuous usage of edible gel-based artificial saliva (30-50 ml/day for at least 5 days per week) | baseline, 2 weeks and 4 weeks after intervention |
| Changes in salivary Potential of Hydrogen ion (pH) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Aroonwan Lam-ubol, DDS, PhD | Srinakharinwirot University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Health, Ministry of Health | Nonthaburi | 11000 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26631691 | Derived | Dalodom S, Lam-Ubol A, Jeanmaneechotechai S, Takamfoo L, Intachai W, Duangchada K, Hongsachum B, Kanjanatiwat P, Vacharotayangul P, Trachootham D. Influence of oral moisturizing jelly as a saliva substitute for the relief of xerostomia in elderly patients with hypertension and diabetes mellitus. Geriatr Nurs. 2016 Mar-Apr;37(2):101-9. doi: 10.1016/j.gerinurse.2015.10.014. Epub 2015 Nov 26. |
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| ID | Term |
|---|---|
| D014987 | Xerostomia |
| D006973 | Hypertension |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D014652 | Vascular Diseases |
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| OTHER_GOV |
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|
The outcome measure will be measured before and 2 and 4 weeks after continuous usage of edible gel-based artificial saliva (30-50 ml/day for at least 5 days per week) |
| baseline, 2 weeks and 4 weeks after intervention |
| Changes in salivary buffering capacity | The outcome measure will be measured before and 2 and 4 weeks after continuous usage of edible gel-based artificial saliva (30-50 ml/day for at least 5 days per week) | baseline, 2 weeks and 4 weeks after intervention |
| Satisfaction of the edible gel-based artificial saliva | All subjects will try a few spoon of the edible gel based saliva and a commercially available inedible gel-based saliva. Then, all subjects will be interviewed for satisfaction of both products and compare the results. | at the first day of trial |
| D002318 |
| Cardiovascular Diseases |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |