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| Name | Class |
|---|---|
| Federal Food Safety and Veterinary Office (Switzerland) | UNKNOWN |
The aim of this study is to monitor iodine nutrition in Switzerland in order to inform the authorities regarding iodine content in iodized salt. As a proxy for the entire population the investigators will study school aged children, pregnant women and women of reproduction age.
In a national sample of school aged children (n=990), pregnant women (n=700) and women of reproductive age (n=700) urinary iodine will be determined in order to assess iodine nutrition in Switzerland. In addition, in both groups of women a blood sample will be taken for the determination of thyroid hormones, iron- and folate status. Questionnaires will be used for the determination of dietary iodine and salt intake as well as sociodemographic parameters.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| School aged children | |||
| Pregnant women | |||
| Women of reproductive age |
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| Measure | Description | Time Frame |
|---|---|---|
| Median urinary iodine concentration in school aged children, pregnant women and women of reproductive age | analysis of urine samples | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Population mean thyroglobulin | Analysis of venous blood samples. Assessed only in women | Baseline |
| Population mean thyroid stimulating hormone | Analysis of venous blood samples. Assessed only in women |
| Measure | Description | Time Frame |
|---|---|---|
| Mean height of school aged children and women of reproductive age | Baseline | |
| Mean weight of school aged children and women of reproductive age | Baseline | |
| Median urinary fluoride |
Inclusion Criteria:
Exclusion Criteria:
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school aged children, 6-12 years pregnant women, 18-44 years women of reproductive age, 18-44 years
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Human Nutrition Laboratory, ETH Zurich | Zurich | 8092 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30843107 | Derived | Andersson M, Hunziker S, Fingerhut R, Zimmermann MB, Herter-Aeberli I. Effectiveness of increased salt iodine concentration on iodine status: trend analysis of cross-sectional national studies in Switzerland. Eur J Nutr. 2020 Mar;59(2):581-593. doi: 10.1007/s00394-019-01927-4. Epub 2019 Mar 1. |
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| Baseline |
| Population mean thyroxine | Analysis of venous blood samples. Assessed only in women | Baseline |
| Median urinary sodium concentration | Baseline |
| Median urinary creatinin concentration | Baseline |
Analyzed in urine samples from school aged children only. |
| Baseline |
| Population mean folate status | Analysis of red blood cell folate and plasma folate in venous blood samples. | Baseline |
| Populations mean iron status | Serum analysis: ferritin, transferrin receptor; in women of reproductive age and pregnant women. | Baseline |
| Individual inflammatory state | Serum analysis of CRP and AGP, analyzed only in women | Baseline |
| Intake of iodine in micro grams per day | iodine intake assessed by food frequency questionnaire, only in women | Baseline |
| % of households with adequate iodine coverage | Salt samples only collected from children (subgroup) | Baseline |