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Eyes of 108 diabetic patients have underwent phacoemulsification and intraocular lens implantation surgery have enrolled. Fifty four eyes have received the conventional postoperative care with steroid drop, whereas the other group (54 eyes) have given a preoperative diclofenac drop four times daily in addition to steroid drop and continued six weeks after surgery. All patients have evaluated by Optical coherence tomography (OCT) preoperatively and days 1, 30, and 90.The outcome measures including best corrected visual acuity (BCVA) and OCT findings were compared in and between both groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| placebo (ARTIFICIAL TEAR) | Placebo Comparator | control group received artificial tear (Sina Darou Laboratories Company, Tehran, Iran) as a placebo every 6 hours. Theses drops continued up to 6 weeks with the same dose after operations. |
|
| diclofenac sodium drop | Active Comparator | case group received diclofenac sodium drop 0.1% (Sina Darou Laboratories Company, Tehran, Iran) every 6 hours.. Theses drops continued up to 6 weeks with the same dose after operations. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prescribe ARTIFICIAL TEAR | Drug | From one week before surgery, and control group received artificial tear (Sina Darou Laboratories Company, Tehran, Iran) as a placebo every 6 hours. Theses drops continued up to 6 weeks with the same dose after operations |
| Measure | Description | Time Frame |
|---|---|---|
| macular thickness changes | Optical coherence tomography (OCT) | preoperatively until 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| best corrected visual acuity (BCVA) changes | LogMAR (Logarithm of the Minimum Angle of Resolution)charts | preoperatively until 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Labbafinejad medical center | Tehran | Iran |
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| Prescribe diclofenac sodium drop 0.1% | Drug | From one week before surgery, case group received diclofenac sodium drop 0.1% (Sina Darou Laboratories Company, Tehran, Iran) every 6 hours.Theses drops continued up to 6 weeks with the same dose after operations |
|