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Establishing the association between biological markers and exercise capacity in continuous-flow left ventricular assist device patients.
The aim of this study is to investigate if specific biological markers can predict exercise capacity in advanced heart failure patients supported with continuous-flow left ventricular assist device patients.
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| Measure | Description | Time Frame |
|---|---|---|
| Biological markers | Analysis of blood will be carried out on all samples simultaneously, expected markers are pro-BNP, MRproANP, copeptin, Gal-3 and proADM. | Blood sampling on study day and samples are subsequently stored frozen. |
| Measure | Description | Time Frame |
|---|---|---|
| Exercise capacity | Exercise capacity will be estimated by peak VO2 measurements on a upright ergometer bike with breath-by-breath gas analysis. | Examination on study day. Patients will only be followed on the day of the study. Exercise testing is performed as the last intervention on the study day. |
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Inclusion Criteria:
Exclusion Criteria:
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Stable CF-LVAD patients.
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| Name | Affiliation | Role |
|---|---|---|
| Finn Gustafsson, MD, PhD | Rigshospitalet, Denmark | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Rigshospitalet. | Copenhagen | Kbh Oe | 2100 | Denmark |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001519 | Behavior |
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Blood samples in biological bank.