Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children.

Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children: A Double Blind Randomized, Placebo- Controlled Trial .

Gelatin tannate possesses astringent, antibacterial, and anti-inflammatory properties. It is increasingly being marketed as an antidiarrheal drug. A randomized, double blind, placebo-control trial was performed to assess the effectiveness of GT in management of children with acute gastroenteritis.

Inclusion Criteria:

• children < 5 years old
• diarrhea (defined as the passage of 3 or more loose or watery stools per day) for > 1 day but < 5 days
• inform consent sign

Exclusion Criteria:

• regularly used antibiotics, probiotics, gelatin tannate, diosmectite, racecadotril within 7 days before admission
• underlying gastrointestinal tract disorder presenting with diarrhea
• breastfeeding >50%
• malnutrition (weight/high <3pc)