Effects of Pectin Supplementation in Diarrhea-predominant Irritable Bowel Syndrome

Therapeutic Effects of Pectin Supplementation in Patients With Diarrhea-predominant Irritable Bowel Syndrome

The purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on clinical symptoms, gut microbiota and the immune status in patients with diarrhea-predominant irritable bowel syndrome

Patients were randomized to receive either pectin or placebo. Treatment consisted of 6 weeks supplementation with pectin (fiber group) or placebo (maltodextrin). We evaluated the clinical symptoms, gut microbiota and the immune markers in two groups.

Inclusion Criteria:

• All patients(age≧18y)
• Admitted for diarrhea-predominant irritable bowel syndrome

Exclusion Criteria:

• Mental disorders
• Cancer
• Inflammatory bowel disease