Clinical Effects of Soluble Dietary Fiber Supplementation

Study of Soluble Dietary Fiber on Colonic Transit Time and Clinical Symptoms in Adults With Slow-transit Constipation

The purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on colonic transit time, clinical symptoms and the gut microbiota in adults with slow-transit constipation.

Patients were randomized to receive either pectin or placebo. Treatment consisted of 4 weeks supplementation with pectin (fiber group) or placebo. We evaluated the colonic transit time, constipation symptoms and fecal bacterial population in two groups.

Inclusion Criteria:

• All patients(age≧18y)
• Admitted for slow-transit constipation were considered eligible

Exclusion Criteria:

• Mental disorders
• Cancer
• Inflammatory bowel disease