Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time

Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time: A Randomized Control Trial

The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on orthodontic treatment time. This is a double-blinded RCT with half the patients receiving treatment from a sham non-functional device, serving as controls, and the other half receiving light therapy treatment from a functional OrthoPulse™. Orthodontic treatment time for the sham-control patients are compared to that of the OrthoPulse™ patients.

Inclusion Criteria:

• Presence of permanent dentition
• Eligible and scheduled for full mouth fixed orthodontic treatment.
• Class I or Class II malocclusion (no more than ½ cusp in Class II)
• Non-extraction in all quadrants
• Non-smoker, non-use of chewing tobacco
• Good oral hygiene
• No adjunct treatment such as extra or intraoral appliances
• Age 12-40

Exclusion Criteria:

• Pregnant females
• Patient is currently enrolled in another clinical study
• Non-steroidal Anti-Inflammatory drug (NSAID) use during study (Acetominophen acceptable)
• Periodontally involved teeth
• Use of bisphosphonates
• Unerupted erupted teeth
• Teeth blocked out of alignment and unable to engage initial arch wire