The purpose of this study is to evaluate the effect of acupuncture protocol involving in Weizhong (BL4) and Huantiao (GB30) points in treating ankylosing spondylitis.

Inclusion Criteria:

• Eligible adult (≥18 years of age) patients
• had a diagnosis of AS for at least 3 months defined as definite by the 1984 modified New York criteria
• Eligible patients also had a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of ≥4 (0-10 cm scale)
• A visual analogue scale (VAS) score for total back pain of ≥4 (0-10 cm scale)

Exclusion Criteria:

• Had received prior Acupuncture therapy
• With complete ankylosis of the spine, defined as the presence of bridging syndesmophytes at all intervertebral levels of the cervical and lumbar spine on lateral view spinal radiographs