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| Name | Class |
|---|---|
| French association for research in cardiology (ARCARD) | UNKNOWN |
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Patients with atrial fibrillation are exposed to a high risk of thrombus in the left atrium that can induce cerebral vascular events or systemic embolisms. This justifies the prescription of anticoagulant therapies in patients with high risk of thromboembolic event. Percutaneous left atrial appendage closure is a new interventional strategy for patients with high risk of cardiovascular events and a counter-indication for long term treatment with anticoagulant agents. However, only few data are available on effectiveness and prognosis of patients treated by this new interventional strategy.
This national database record per-procedure and follow-up data of patients treated by left atrial appendage closure.
This database is strictly observational.
Percutaneous left atrial appendage closure is performed only for the purpose of patient care. No specific intervention is performed specifically for the database. Neither left atrial appendage closure procedure nor patient follow up are modified by patient inclusion in the database.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Left Atrial Appendage Closure | Patients with atrial fibrillation and counter-indication to anticoagulant therapy referred for percutaneous Left Atrial Appendage Closure in routine care |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Percutaneous Left Atrial Appendage Closure in routine care | Other | The inclusion in the database induces no specific intervention. Percutaneous Left Atrial Appendage Closure is performed for patient care. No specific intervention is performed specifically for the database. Neither left atrial appendage closure procedure nor patient follow up are modified by patient inclusion in the database. |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of the rate of thromboembolic events related to atrial fibrillation in patients treated by left atrial appendage closure in daily practice in France | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of patient management in daily practice after left atrial appendage closure (number of echocardiography procedures) | 1 year | |
| Death rate from cardiovascular disease after left atrial appendage closure | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
none
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All patients referred for percutaneous Left Atrial Appendage Closure to one of the French centers involved in this database
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| Name | Affiliation | Role |
|---|---|---|
| Emmanuel Teiger, MD, PhD | emmanuel.teiger@hmn.aphp.fr | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Henri Mondor Hospital | Créteil | 94000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34051135 | Derived | Teiger E, Thambo JB, Defaye P, Hermida JS, Abbey S, Klug D, Juliard JM, Spaulding C, Armero S, Champagnac D, Bhugaloo H, Ternacle J, Lellouche N, Audureau E, Le Corvoisier P; French national Left Atrial Appendage Closure registry (FLAAC) investigators. Left atrial appendage closure for stroke prevention in atrial fibrillation: Final report from the French left atrial appendage closure registry. Catheter Cardiovasc Interv. 2021 Oct;98(4):788-799. doi: 10.1002/ccd.29795. Epub 2021 May 29. | |
| 29540492 |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| Unexplained Death rate after left atrial appendage closure | 1 year |
| Adverse events related to the procedure | 1 year |
| Cost of the procedure of left atrial appendage closure | Costs will be assessed for the duration of hospital stay, an expected average of 3 days |
| Cost of patient follow-up after left atrial appendage closure | 1 year |
| Assessment of patient medical treatment in daily practice after left atrial appendage closure (percentage of patients with antiplatelet drugs) | 1 year |
| Derived |
| Teiger E, Thambo JB, Defaye P, Hermida JS, Abbey S, Klug D, Juliard JM, Pasquie JL, Rioufol G, Lepillier A, Elbaz M, Horvilleur J, Brenot P, Pierre B, Le Corvoisier P; French National Left Atrial Appendage Closure Registry (FLAAC) Investigators. Percutaneous Left Atrial Appendage Closure Is a Reasonable Option for Patients With Atrial Fibrillation at High Risk for Cerebrovascular Events. Circ Cardiovasc Interv. 2018 Mar;11(3):e005841. doi: 10.1161/CIRCINTERVENTIONS.117.005841. |
| D013568 |
| Pathological Conditions, Signs and Symptoms |