Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women

Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women

The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.

An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.

Tissue is analysed and compared for changes in gene expression profile using Seq RNA

Inclusion Criteria:

• Fertile women
• Age: 18-40 years
• BMI: 18-32
• Regular menstrual cycle
• No use of hormonal contraceptives or IUD the last 3 months

Exclusion Criteria:

• Patients in need of a interpreter
• Suspected intrauterine abnormalities
• Pregnancy