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The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7.
Tissue is analysed and compared for changes in gene expression profile using Seq RNA
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| endometrial biopsy | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| endometrial biopsy | Procedure |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Gene Expression of the Endometrium after an endometrial biopsy | An endometrial biopsy is done at cycle day LH+7 and repeated in the next cycle at cycle day LH+7. Endometrial tissue is analysed for changes in gene expression profile of various chemokines and cytokines using RNA Sequencing technology | 1 month between each biopsy |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Axel Forman, MD, DMsc | Departement of Gynaecology and Obstetrics, Aarhus University | Study Director |
| Mia Steengaard Olesen, MD | Fertility Clinic Horsens Hospital, Aarhus University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fertility Clinic Horsens Hospital | Horsens | Denmark |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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