Supplementation of Vitamin D in Patients With Type 2 Diabetes and Hypertension

Supplementation of Vitamin D in Patients With Type 2 Diabetes and Hypertension: Randomized Clinical Trial

In patients with type 2 diabetes, the effects on blood pressure of vitamin D has been shown to be variable. Thus, the goal of this proposal is to evaluate the effect of vitamin D supplementation in patients with type 2 diabetes and hypertension

Inclusion Criteria:

• type 2 diabetes
• hypovitaminosis D
• hypertension

Exclusion Criteria:

• pregnant or lactating
• patients using vitamin D supplementation
• using drugs that interfere on vitamin D metabolism (corticosteroids, anticonvulsants)
• illicit drug use
• diseases such as chronic renal failure (serum creatinine greater than 2.0 mg/dl)
• liver cirrhosis
• alcoholism
• dementia
• malignant disease that compromises the 5-year survival,
• digestive tract (malabsorption) diseases
• BMI> 40 kg / m2