Transfusion Requirements After Head Trauma

Transfusion Requirements After Head Trauma

TRAHT is a pilot randomized clinical trial designed to evaluate safety and feasibility of two red blood cells transfusion thresholds in moderate or severe traumatic brain injured patients

Inclusion Criteria:

• Age equal to or greater than 18 years
• Moderate or severe traumatic brain injury, defined as Glasgow coma scale less than or equal to 12 at hospital admission
• Hemoglobin lower than 9.0 g/dL within 7 days from hospital admission

Exclusion Criteria:

• Glasgow coma scale equal to 3 with dilated pupils bilaterally
• Previous neurological sequelae
• Pregnant women
• Jehovah's Witnesses
• Hemorrhagic shock at randomization
• Moribund patients
• Unable to provide consent